PROBLEM TO BE SOLVED: To provide methods for producing telmisartan-containing tablets in which dissolution of telmisartan is improved.SOLUTION: A method for producing a tablet containing telmisartan, a diluent, meglumine, and an excipient comprises a first granulation step of granulating telmisartan, a diluent, and meglumine to obtain a primary granulated material, a second granulation step of granulating the primary granulated material and a diluent to obtain a second granulated material, a mixing step of mixing the second granulated material and an excipient to obtain a mixture, and a tableting step of tableting the mixture to obtain a tablet.SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【課題】錠剤中のテルミサルタンの溶出性が向上するテルミサルタン含有錠剤の製造方法を提供する。【解決手段】テルミサルタンと、希釈剤と、メグルミンと、賦形剤と、を含む錠剤の製造方法であって、テルミサルタンと、希釈剤と、メグルミンとを造粒して一次造粒物を得る一次造粒工程と、前記一次造粒物と、希釈剤とを造粒して二次造粒物を得る二次造粒工程と、前記二次造粒物と、賦形剤とを混合して混合物を得る混合工程と、前記混合物を打錠して錠剤を得る打錠工程と、を含む錠剤の製造方法。【選択図】なし
