KAUTZ, ULRICH,SCHMIDT, BEATE,FLOCKERZI, DIETER,HATZELMANN, ARMIN,ZITT, CHRISTOF,MARX, DEGENHARD,KLEY, HANS-PETER,BARSIG, JOHANNES
申请号：
DK12196702
公开号：
DK2589599T3
申请日:
2005.03.02
申请国别(地区):
DK
年份:
2014
代理人:
摘要：
Compounds of formula I in which R1 is methoxy, R2 is methoxy, ethoxy, difluoromethoxy or 2,2-difluoroethoxy, R3 is hydrogen, R31 is hydrogen, R4 is -O-R41, in which R41 is hydrogen, R5 is hydrogen, Har is substituted by R6 and R7, and is pyridinyl, in which R6 is oxo, and R7 is methyl, or an enantiomer, a salt, a N-oxide or a salt of an enantiomer or N-oxide thereof are novel effective PDE4 inhibitors.
