MARX, Degenhard,FLOCKERZI, Dieter,KAUTZ, Ulrich,ZITT, Christof,HATZELMANN, Armin,SCHMIDT, Beate,KLEY, Hans-Peter,Barsig, Johannes
申请号：
MEP11314
公开号：
ME01955B
申请日:
2005.03.02
申请国别(地区):
ME
年份:
2015
代理人:
摘要：
Compounds of formula I in which R1 is methoxy, R2 is methoxy, ethoxy, difluoromethoxy or 2,2-difluoroethoxy, R3 is hydrogen, R31 is hydrogen, R4 is -O-R41, in which R41 is hydrogen, R5 is hydrogen, Har is substituted by R6 and R7, and is pyridinyl, in which R6 is oxo, and R7 is methyl, or an enantiomer, a salt, a N-oxide or a salt of an enantiomer or N-oxide thereof are novel effective PDE4 inhibitors.text
