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COMPOSES ET COMPOSITIONS POUR INHIBER L'ACTIVITE D'ABL1, ABL2 ET BCR-ABL1
专利权人:
NOVARTIS AG
发明人:
DODD, STEPHANIE KAY,FURET, PASCAL,GROTZFELD, ROBERT MARTIN,JONES, DARRYL BRYNLEY,MANLEY, PAUL,MARZINZIK, ANDREAS,PELLE, XAVIER FRANCOIS ANDRE,SALEM, BAHAA,SCHOEPFER, JOSEPH,JAHNKE, WOLFGANG
申请号:
CA2868958
公开号:
CA2868958A1
申请日:
2013.05.09
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention relates to compounds of formula (I): in which Y, Y1, R1, R2, R3 and R4 are defined in the Summary of the Invention; capable of inhibiting the activity of BCR-ABL1 and mutants thereof. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds in the treatment of cancers.
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中国工程科技知识中心
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