Dodd, Stephanie Kay,Furet, Pascal,Grotzfeld, Robert Martin,Jones, Darryl Brynley,Manley, Paul,Marzinzik, Andreas,Pelle, Xavier Francois Andre,Salem, Bahaa,Schoepfer, Joseph,Jahnke, Wolfgang
申请号：
HRP20180695
公开号：
HRP20180695T1
申请日:
2018.05.03
申请国别(地区):
HR
年份:
2018
代理人:
摘要：
The present invention relates to compounds of formula (I): in which Y, Y1, R1, R2, R3 and R4 are defined in the Summary of the Invention； capable of inhibiting the activity of BCR-ABL1 and mutants thereof. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds in the treatment of cancers.
