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BENZAMIDE DERIVATIVES FOR INHIBITING THE ACTIVITY OF ABL1, ABL2 AND BCR-ABL1 ABL1ABL2 BCR-ABL1
专利权人:
NOVARTIS AG
发明人:
DODD STEPHANIE KAY,FURET PASCAL,GROTZFELD ROBERT MARTIN,JONES DARRYL BRYNLEY,MANLEY PAUL,MARZINZIK ANDREAS,PELLE XAVIER FRANCOIS ANDRE,SALEM BAHAA,SCHOEPFER JOSEPH,JAHNKE WOLFGANG
申请号:
AP2014007992
公开号:
AP3613A
申请日:
2013.05.09
申请国别(地区):
AP
年份:
2016
代理人:
摘要:
The present invention relates to compounds of formula (I): in which Y, Y1, R1, R2, R3 and R4 are defined in the Summary of the Invention; capable of inhibiting the activity of BCR-ABL1 and mutants thereof. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds in the treatment of cancers.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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