The present invention patent (pi) concerns a process of obtaining solid, fusion -emulsification lipid microparticles using lipid and tensoats, such as lecithins and emulsificants, as well as microparticles obtained. Thus, the said process can be categorised as a pharmaceutical and /or pharmacologically active product in view of the fact that it is a process of obtaining solid lipid microparticles preferably using cetylpalmitate as lipid, and before that it has application of The areas of pharmacy, medicine, biomedicine, chemistry and biotechnology. Yet,This invention describes the encapsulation of the mesalazine drug in microparticles for preferential treatment of inflammatory bowel disease. For the development of said process of obtaining solid, microlipid microparticles encapsulating fusion -emulsification mesalazine and the microparticles obtained, the following steps from 1 to 3 shall be considered: (1) preparation of pre -emulsion； (2) fusion -emulsification； and (3) Cooling. Finally, it is evident that the microencapsulation of mesalazine with adequate lipid and surfactants allows for better targeting and release of the drug into the target tissue, and consequently,Increases its bioavailability and therapeutic effect. In addition, the end product may be an active ingredient for new pharmaceutical formulations.a presente patente de invenção (pi) diz respeito a um processo de obtenção de micropartículas lipídicas sólidas por fusão-emulsificação, utilizando lipídio e tensoativos, como lecitinas e emulsificantes, bem como as micropartículas obtidas. assim, o dito processo pode ser categorizada como um produto farmacêutico e/ou farmacologicamente ativo tendo em vista que trata-se de um processo de obtenção de micropartículas lipídicas sólidas preferencialmente utilizando o cetilpalmitato como lipídio, e, diante disso possui aplicação direta nas áreas de farmácia, medicina, biomedicina, química e biotecnologia. ainda, esta invenção descreve a encapsulação do fármaco
