ZHANG, Yong,MCDONALD, Ivar M.,CHOWDARI, Naidu S.,HUYNH, Tram N.,BORZILLERI, Robert M.,GANGWAR, Sanjeev
申请号:
ES16703196
公开号:
ES2783624T3
申请日:
2016.01.13
申请国别(地区):
ES
年份:
2020
代理人:
摘要:
Benzodiazepine dimers having a structure represented by wherein R1 is wherein the variables in formulae (I), (Ia), and (Ib) are as defined in the application. Such dimers are useful as anti-cancer agents, especially when used in an antibody-drug conjugate (ADC).