Yong Zhang,Robert M. Borzilleri,Andrew J. Tebben,Erik M. Stang,Andrew F. Donnell,Gretchen M. Schroeder,Heidi L. Perez,Donna D. Wei
申请号：
US15606512
公开号：
US09902740B2
申请日:
2017.05.26
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Macrocyclic benzodiazepine dimers having a structure represented by formula Iwhere A and B are independently according to formulae Ia or Iband the other variables in formulae I, Ia, and Ib are as defined in the application. Such dimers are useful as anti-cancer agents, especially when used as the drug component in an antibody-drug conjugate (ADC).
