Zhang, Yong,Borzilleri, Robert M.,Tebben, Andrew J.,Stang, Erik M.,Donnell, Andrew F.,Schroeder, Gretchen M.,Perez, Heidi L.,Wei, Donna D.
申请号：
AU2016284340
公开号：
AU2016284340A1
申请日:
2016.06.22
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
Macrocyclic benzodiazepine dimers having a structure represented by formula (I) where A and B are independently according to formulae (Ia) or (Ib) ]； and the other variables in formulae (I), (Ia), and (Ib) are as defined in the application. Such dimers are useful as anti-cancer agents, especially when used as the drug component in an antibody-drug conjugate (ADC).
