BENZODIAZEPINE DIMERS, CONJUGATES THEREOF, AND METHODS OF MAKING AND USING

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专利权人:

BRISTOL-MYERS SQUIBB COMPANY

发明人:

ZHANG, Yong,MCDONALD, Ivar M.,CHOWDARI, Naidu S.,HUYNH, Tram N.,BORZILLERI, Robert M.,GANGWAR, Sanjeev

申请号：

SG11201705646X

公开号：

SG11201705646XA

申请日:

2016.01.13

申请国别(地区):

SG

年份:

2017

代理人:

摘要：

Benzodiazepine dimers having a structure represented by wherein R1 is wherein the variables in formulae (I), (Ia), and (Ib) are as defined in the application. Such dimers are useful as anti-cancer agents, especially when used in an antibody-drug conjugate (ADC).

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中国工程科技知识中心

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http://www.ckcest.cn/home/