The present disclosure relates to a flexographic printing device and a method of simultaneously printing at least two material webs having different thicknesses in the printing device. The flexographic printing device comprises a printing unit comprising a printing roller carrying on a surface thereof an image to be printed, an impression roller and an anilox roller adapted to feed printing ink from a printing ink chamber onto the printing cliché mounted on the printing roller. The printing unit is configured for simultaneously printing at least two material webs having different thicknesses, by means of adjusting the radial extension of the surface of the printing roller, impression cylinder and/ anilox roller in respect of the material web to be printed.