Heyes, James,Holland, Richard J.,Judge, Adam,Lee, Amy C. H.,Martin, Alan D.,Snead, Nicholas Michael,Thi, Emily P.,Wood, Mark,Ye, Xin
申请号：
AU2018250553
公开号：
AU2018250553A1
申请日:
2018.04.10
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
The invention provides certain nucleic acids (e.g., double stranded siRNA molecules), as well as conjugates that comprise a targeting moiety, a double stranded siRNA, and optional linking groups. Certain embodiments also provide synthetic methods useful for preparing the conjugates. The conjugates are useful to target therapeutic double stranded siRNA to the liver and to treat liver diseases including hepatitis (e.g. hepatitis B and hepatitis D).
