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PARTICULES DE TYPE VIRAL AVEC REVÊTEMENT HAUTE DENSITÉ POUR LA PRODUCTION D'ANTICORPS NEUTRALISANTS
专利权人:
Fundació Privada Institut de Recerca de la SIDA-Caixa
发明人:
申请号:
EP16382364.4
公开号:
EP3275462A1
申请日:
2016.07.27
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The invention relates to a fusion protein comprising a HIV gag polypeptide or a functionally equivalent variant thereof and an immunogenic polypeptide, wherein the immunogenic polypeptide is located N-terminal to the HIV gag polypeptide or to the functionally equivalent variant thereof, to a polynucleotide, a vector, a host cell and an immunogenic composition or vaccine composition and the their use in medicine, particularly in in the prevention and/or treatment of a disease caused by an infection in a subject, wherein the infection is by a pathogen which contains the immunogenic polypeptide forming part of the fusion protein or a region thereof.
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