WINTERS, MICHAEL P.,BRANUM, SHAWN,FAWZY, NAGY E.,KANG, FU-AN,REUMAN, MICHAEL,RUSSELL, RONALD K.,TELEHA, CHRISTOPHER A.,SUI, ZHIHUA
申请号：
CA2869647
公开号：
CA2869647A1
申请日:
2013.04.05
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention comprises compounds of Formula (I). Formula (I) wherein: R0, R1, R2, R3, R4, R5, and A are as defined in the specification. The invention also comprises a method of preventing, treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is type II diabetes, obesity and asthma. The invention also comprises a method of inhibiting CCR2 activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula (I).
