Michael P. Winters,Nagy E. Fawzy,Fu-An Kang,Zhihua Sui
申请号:
US13856666
公开号:
US08822460B2
申请日:
2013.04.04
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention comprises compounds of Formula (I).wherein: R0, R1, R2, R3, R4, R5, and A are as defined in the specification. The invention also comprises a method of preventing, treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is type II diabetes, obesity and asthma. The invention also comprises a method of inhibiting CCR2 activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula (I).