CAI, CHAOZHONG,MCCOMSEY, DAVID F.,SUI, ZHIHUA,KANG, FU AN
申请号：
CA2879126
公开号：
CA2879126A1
申请日:
2013.07.16
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention comprises compounds of Formula (I). Formula (I) wherein: R1, R2, R3, R4, R5, Z1 and Z2 are as defined in the specification. The invention also comprises a method of preventing, treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is type II diabetes, obesity and asthma. The invention also comprises a method of inhibiting CCR2 activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula (I).
