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Cyclohexyl-azetidinyl antagonists of CCR2
专利权人:
Janssen Pharmaceutica NV
发明人:
James C. Lanter,Thomas P. Markotan,Nalin Subasinghe,Zhihua Sui
申请号:
US13947340
公开号:
US09062048B2
申请日:
2013.07.22
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention comprises compounds of Formula I.wherein: R1, R2, R4, J, Q, and A are as defined in the specification. The invention also comprises a method of preventing, treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is type II diabetes, obesity and asthma. The invention also comprises a method of inhibiting CCR2 activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula I.
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