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Cyclohexyl-azetidinyl antagonists of CCR2
专利权人:
James C. Lanter;Xuqing Zhang;Zhihua Sui
发明人:
Xuqing Zhang,Zhihua Sui,James C. Lanter
申请号:
US13156450
公开号:
US08436023B2
申请日:
2011.06.09
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention comprises compounds of Formula (I).wherein: R1, R2, X, and Z are as defined in the specification. The invention also comprises a method of preventing, treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is type II diabetes, obesity and asthma. The invention also comprises a method of inhibiting CCR2 activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula (I).
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