PROBLEM TO BE SOLVED: To provide a method for producing sericin peptide that can be effectively applied to cosmetic products or medicinal products.SOLUTION: Sericin peptide is produced basically by primarily fermenting raw-material sericin to which minerals are added, secondarily fermenting the sericin thereafter, maturing the secondarily fermented sericin, and filtering and extracting sericin peptide. More specifically, minerals and purified water are added and mixed to the previously sterilized raw-material sericin, and next, 10-30 wt.% of Aspergilli of the genus Aspergillus and carbohydrate are added to the raw-material mixture a plurality of times, and the mixture is retained at prescribed temperature to be primarily fermented. Then, 10-20 wt.% of lactic bacteria of the genus Streptococcus or the genus Lactobacillus and acetic acid bacteria individually or their mixture and carbohydrate are added to the primarily fermented sericin a plurality of times, and the mixture is retained at prescribed temperature to be secondarily fermented. Further, the secondarily fermented sericin is matured at 35-40°C, and after that, sericin peptide is filtered and extracted from the matured sericin. Thus produced sericin peptide can be easily applied to cosmetic products and medicinal products, etc.COPYRIGHT: (C)2012,JPO&INPIT【課題】化粧品、医療品などへの応用を好適に行うことができるセリシンペプチドを製造する方法を提供する。【解決手段】ミネラルを添加した原料セリシンを一次醗酵させたのち二次醗酵させ、さらにこの二次醗酵セリシンを熟成して濾過抽出することを基本とするものであり、具体的には、予め殺菌した原料セリシンにミネラルと浄化水を加えて混合し、つぎにこの原料混合物にアスペルギルス属の麹菌10重量%~30重量%と糖質を複数回加えるとともに所定温度に保持して一次醗酵させ、この一次発酵セリシンにストレプトコックス属またはラクトバチルス属の乳酸菌、酢酸菌を単独でまたはこれらの混合物10重量%~20重量%と糖質を複数回を加えて所定温度に保持することにより二次醗酵させ、さらに二次発酵セリシンを35℃~40℃で熟成したのちこれを濾過抽出する。これにより化粧品、医療品などへの応用が容易となる。【選択図】図1
