您的位置: 首页 > 农业专利 > 详情页

PLEUROMUTILIN DERIVATIVES FOR THE TREATMENT OF DISEASES MEDIATED BY MICROBES
专利权人:
Nabriva Therapeutics AG
发明人:
Rosemarie MANG,Werner HEILMAYER,Rudolf BADEGRUBER,Dirk B. STRICKMANN,Rodger NOVAK,Mathias FERENCIC,Atchyuta Rama Chandra Murty BULUSU
申请号:
US15480756
公开号:
US20170266194A1
申请日:
2017.04.06
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A compound of formula (I) wherein n is 0 to 4; m is 0 or 1 with the proviso that the sulphur atom and R3 are in vicinal position (if m=0 then R3 is in position 2′, and if m=1 then R3 is on position 1′); R is ethyl or vinyl; R1 is hydrogen or (C1-6)alkyl; R2 is hydrogen or—(C3-6)cycloalkyl, or—unsubstituted (C1-6)alkyl, or—(C1-6)alkyl substituted by one or more of—hydroxy; preferably one or two,—methoxy,—halogen,—(C3-6)cycloalkyl, or R1 and R2 together with the nitrogen atom to which they are attached form a 5 to 7 membered heterocyclic ring containing at least 1 nitrogen atom or 1 nitrogen and 1 additional heteroatome e. g. selected from N or O, or R1 is hydroxy and R2 is formyl; R3 is OH, OR4, a halogen atom, or—with the proviso that R3 is bound to 2′ R3 represents —O—(CH2)P—O— with p is 2 or 3; R4 is unsubstituted (C1-6)alkyl or (C3-6)cycloalkyl.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充