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IRON OXIDE NANOCAPSULE, METHOD OF MANUFACTURING THE SAME, AND MRI CONTRAST AGENT USING THE SAME
专利权人:
发明人:
申请号:
EP11822141.5
公开号:
EP2621852A2
申请日:
2011.08.31
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
Provided is an iron oxide nanocapsule which has extremely excellent water dispersibility, which is very stable in the body and which has very excellent MRI contrast ability, a method of manufacturing the same, and an MRI contrast agent using the same. The method of manufacturing the iron oxide nanocapsule includes the steps of: thermally decomposing an iron complex to prepare hydrophobic ligand-bonded iron oxide nanoparticles and encapsulating the hydrophobic ligand-bonded iron oxide nanoparticles by a carboxymethyldextrandodecylamine conjugate encapsulation material or a dextran-linoleic acid conjugate encapsulation material to form an iron oxide nanocapsule.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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