KWON, EUN BYUL,JEON, BONG-SIK,KIM, EUNG GYU,PARK, JU YOUNG,MYEONG, WAN JAE
申请号：
EP11822141
公开号：
EP2621852A4
申请日:
2011.08.31
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
Provided is an iron oxide nanocapsule which has extremely excellent water dispersibility, which is very stable in the body and which has very excellent MRI contrast ability, a method of manufacturing the same, and an MRI contrast agent using the same. The method of manufacturing the iron oxide nanocapsule includes the steps of: thermally decomposing an iron complex to prepare hydrophobic ligand-bonded iron oxide nanoparticles and encapsulating the hydrophobic ligand-bonded iron oxide nanoparticles by a carboxymethyldextrandodecylamine conjugate encapsulation material or a dextran-linoleic acid conjugate encapsulation material to form an iron oxide nanocapsule.
