IRON OXIDE NANOCAPSULES, METHOD OF MANUFACTURING THE SAME, AND MRI CONTRAST AGENT USING THE SAME

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专利权人:

发明人:

申请号：

EP11822109.2

公开号：

EP2611730A2

申请日:

2011.08.30

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

Provided are iron oxide nanocapsules for an MRI contrast agent having high contrast, in which a plurality of iron oxide nanoparticles having a hydrophobic ligand attached thereto are encapsulated in an encapsulation material including a biodegradable polymer and a surfactant, and which satisfy Relations 1, 2, 3, 4 and 5 below. Also a method of manufacturing the iron oxide nanocapsules is provided. 5@100*Dmu(IO)/C omega(IO)[Relation 1] 2.5@100*Dmu(Cap)/C omega(Cap)[Relation 2] 0.5 wt %@F(IO)@50 wt %[Relation 3] 1 nm@Dmu(IO)@25 nm[Relation 4] 50 nm@Dmu(Cap)@200 nm[Relation 5]

来源网站：

中国工程科技知识中心

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