Eun Byul Kwon,Bong Sik Jeon,Eung Gyu Kim,Ju Young Park,Wan Jae Myeong
申请号：
US13818734
公开号：
US20140328768A1
申请日:
2011.08.31
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Provided is an iron oxide nanocapsule which has extremely excellent water dispersibility, which is very stable in the body and which has very excellent MRI contrast ability, a method of manufacturing the same, and an MRI contrast agent using the same. The method of manufacturing the iron oxide nanocapsule includes the steps of: thermally decomposing an iron complex to prepare hydrophobic ligand-bonded iron oxide nanoparticles and encapsulating the hydrophobic ligand-bonded iron oxide nanoparticles by a carboxymethyldextrandodecylamine conjugate encapsulation material or a dextran-linoleic acid conjugate encapsulation material to form an iron oxide nanocapsule.
