GLAXOSMITHKLINE INVESTIGACION Y DESARROLLO S.L.;BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM;MONASH UNIVERSITY;MEDICINES FOR MALARIA VENTURE MMV;UNIVERSITY OF WASHINGTON
发明人:
RATHOD, PRADIPSINH, K. PK,FLOYD, DAVID D,BORROWS, JEREMY J,MARWAHA, ALKA A,GUJJAR, RAMESH R,COTERON-LOPEZ, JOSE J-,PHILLIPS, MARGARET M,CHARMAN, SUSAN SA,MATTHEWS, DAVID D,.拉索德,.弗洛伊德,.布羅斯,.馬瓦哈,.古加,.科特隆-洛佩茲,.菲利普斯,.查曼,MA
申请号：
HK13101950.1
公开号：
HK1174639B
申请日:
2013.02.15
申请国别(地区):
HK
年份:
2016
代理人:
摘要：
Inhibitors of parasitic dihydroorotate dehydrogenase enzyme (DHOD) are candidate therapeutics for treating malaria. Illustrative of such therapeutic agents include the compound: and a triazolopyrimidine class of compounds that conform to Formula IX: and their solvates, stereoisomers, tautomers and pharmaceutically acceptable salts.
