GLAXOSMITHKLINE INVESTIGACION Y DESARROLLO, S.L.;MONASH UNIVERSITY;UNIVERSITY OF WASHINGTON;BOARD OF REGENTS;BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM; THE UNIVERSITY OF TEXAS SYSTEM;MMV MEDICINES FOR MALARIA VENTURE
发明人:
申请号：
PT10821105
公开号：
PT2483274E
申请日:
2010.09.28
申请国别(地区):
PT
年份:
2015
代理人:
摘要：
Inhibitors of parasitic dihydroorotate dehydrogenase enzyme (DHOD) are candidate therapeutics for treating malaria. Illustrative of such therapeutic agents include the compound: and a triazolopyrimidine class of compounds that conform to Formula IX: and their solvates, stereoisomers, tautomers and pharmaceutically acceptable salts.
