Board of Regents, The University of Texas System;Glaxosmithkline Investigacion y Desarrollo, S.L.;Monash University;MMV Medicines for Malaria Venture;University of Washington
发明人:
RATHOD, PRADIPSINH K.,FLOYD, DAVID,BURROWS, JEREMY,MARWAHA, ALKA,GUJJAR, RAMESH,COTERON-LOPEZ, JOSE,PHILLIPS, MARGARET,CHARMAN, SUSAN A.,MATTHEWS, DAVID
申请号:
PL10821105
公开号:
PL2483274T3
申请日:
2010.09.28
申请国别(地区):
PL
年份:
2015
代理人:
摘要:
Inhibitors of parasitic dihydroorotate dehydrogenase enzyme (DHOD) are candidate therapeutics for treating malaria. Illustrative of such therapeutic agents include the compound: and a triazolopyrimidine class of compounds that conform to Formula IX: and their solvates, stereoisomers, tautomers and pharmaceutically acceptable salts.