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ANTI-MALARIJSKI AGENSI KAO INHIBITORI DIHIDROOROTAT DEHIDROGENAZE
专利权人:
Board of Regents, The University of Texas System;Glaxosmithkline Investigacion y Desarrollo, S.L.;Monash University;MMV Medicines for Malaria Venture;University of Washington
发明人:
RATHOD, Pradipsinh, K.,FLOYD, David,BURROWS, Jeremy,MARWAHA, Alka,GUJJAR, Ramesh,COTERON-LOPEZ, Jose,PHILLIPS, Margaret,CHARMAN, Susan, A.,MATTHEWS, David
申请号:
MEP815
公开号:
ME02020B
申请日:
2010.09.28
申请国别(地区):
ME
年份:
2015
代理人:
摘要:
Inhibitors of parasitic dihydroorotate dehydrogenase enzyme (DHOD) are candidate therapeutics for treating malaria. Illustrative of such therapeutic agents include the compound: and a triazolopyrimidine class of compounds that conform to Formula IX: and their solvates, stereoisomers, tautomers and pharmaceutically acceptable salts.text
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