BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM;MONASH UNIVERSITY;MMV MEDICINES FOR MALARIA VENTURE;UNIVERSITY OF WASHINGTON;GLAXOSMITHKLINE INVESTIGACION Y DESARROLLO, S.L.
发明人:
RATHOD, PRADIPSINH K.,FLOYD, DAVID,BURROWS, JEREMY,MARWAHA, ALKA,GUJJAR, RAMESH,COTERON-LOPEZ, JOSE,PHILLIPS, MARGARET,CHARMAN, SUSAN A.,MATTHEWS, DAVID
申请号:
HRP20150066
公开号:
HRP20150066T1
申请日:
2015.01.19
申请国别(地区):
HR
年份:
2015
代理人:
摘要:
Inhibitors of parasitic dihydroorotate dehydrogenase enzyme (DHOD) are candidate therapeutics for treating malaria. Illustrative of such therapeutic agents include the compound: and a triazolopyrimidine class of compounds that conform to Formula IX: and their solvates, stereoisomers, tautomers and pharmaceutically acceptable salts.