Pradipsinh K. Rathod;David Floyd;Jeremy Burrows;Alka Marwaha;David Matthews;Margaret Phillips;Susan A. Charman;Jose Coteron-Lopez;Ramesh Gujjar
发明人:
Pradipsinh K. Rathod,David Floyd,Jeremy Burrows,Alka Marwaha,Ramesh Gujjar,Jose Coteron-Lopez,Margaret Phillips,Susan A. Charman,David Matthews
申请号：
US13499031
公开号：
US20120302586A1
申请日:
2010.09.28
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Inhibitors of parasitic dihydroorotate dehydrogenase enzyme (DHOD) are candidate therapeutics for treating malaria. Illustrative of such therapeutic agents include the compound:and a triazolopyrimidine class of compounds that conform to Formula IX:and their solvates, stereoisomers, tautomers and pharmaceutically acceptable salts.
