THE UNIVERSITY OF BRITISH COLUMBIA;British Columbia Cancer Agency Branch
发明人:
Raymond ANDERSEN,Marianne Dorothy SADAR,Kunzhong JIAN,Nasrin R. MAWJI,Jun WANG,Carmen Adriana BANUELOS,Yu-Chi YANG
申请号：
US15489162
公开号：
US20170298033A1
申请日:
2017.04.17
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Compounds having a structure of Formula I:or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, R3, R11a, R11b, R11c, R11d, and X, are as defined herein, are provided. Uses of such compounds for modulating androgen receptor activity, imaging diagnostics in cancer and therapeutics, and methods for treatment of subjects in need thereof, including prostate cancer are also provided.
