Nasrin R. MAWJI;Britis;Carmen Adriana BANUELOS;Marianne Dorothy SADAR;Kunzhong JIAN;The University of British Columbia University- Industry Liaison Office;Javier Garcia FERNANDEZ;Raymond John ANDERSEN
发明人:
Raymond John ANDERSEN,Javier Garcia FERNANDEZ,Kunzhong JIAN,Marianne Dorothy SADAR,Nasrin R. MAWJI,Carmen Adriana BANUELOS
申请号：
US15543389
公开号：
US20180327368A1
申请日:
2016.01.13
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Compounds having a structure of Formula I: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, R3, R11a, R11b, R11c, R11d, X, n1, n2, and n3 are as defined herein, are provided. Uses of such compounds for modulating androgen receptor activity, imaging diagnostics in cancer and therapeutics, and methods for treatment of subjects in need thereof, including prostate cancer are also provided.
