The University of British Columbia University-Industry Liaison Office;BRITISH COLUMBIA CANCER AGENCY BRANCH
发明人:
申请号:
IL25339417
公开号:
IL253394D0
申请日:
2017.07.10
申请国别(地区):
IL
年份:
2017
代理人:
摘要:
Compounds having a structure of Formula I: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, R3, R11a, R11b, R11c, R11d, X, n1, n2, and n3 are as defined herein, are provided. Uses of such compounds for modulating androgen receptor activity, imaging diagnostics in cancer and therapeutics, and methods for treatment of subjects in need thereof, including prostate cancer are also provided.