YONG XU,BENJAMIN GARY BRENNING,STEVEN G. KULTGEN,XIAOHUI LIU,MICHAEL SAUNDERS,KOC-KAN HO
申请号:
HK14111875.1
公开号:
HK1198360A
申请日:
2014.11.24
申请国别(地区):
HK
年份:
2015
代理人:
摘要:
The present invention provides protein kinase having one of the following structures (I), (II) or (III): or a stereoisomer, prodrug, tautomer or pharmaceutically acceptable salt thereof, wherein R, R1, R2 and X are as defined herein. Compositions and methods for using the same in the treatment of cancer, autoimmune, inflammatory and other Pim kinase-associated conditions are also disclosed.