The University of British Columbia;British Columbia Cancer Agency Branch
发明人:
Raymond John Andersen,Javier Garcia Fernandez,Kunzhong Jian,Marianne Dorothy Sadar,Nasrin R. Mawji,Carmen Adriana Banuelos
申请号：
US16864479
公开号：
US20200325106A1
申请日:
2020.05.01
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Compounds having a structure of Formula I:or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, R3, R11a, R11b, R11c, R11d, X, n1, n2, and n3 are as defined herein, are provided. Uses of such compounds for modulating androgen receptor activity, imaging diagnostics in cancer and therapeutics, and methods for treatment of subjects in need thereof, including prostate cancer are also provided.
