THE UNIVERSITY OF BRITISH COLUMBIA UNIVERSITY-INDUSTRY LIAISON OFFICE;BRITISH COLUMBIA CANCER AGENCY BRANCH
发明人:
FERNANDEZ, JAVIER GARCIA,ANDERSEN, RAYMOND JOHN,BANUELOS, CARMEN ADRIANA,JIAN, KUNZHONG,MAWJI, NASRIN R.,SADAR, MARIANNE DOROTHY
申请号：
CA2973036
公开号：
CA2973036A1
申请日:
2016.01.13
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Compounds having a structure of Formula I: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, R3, R11a, R11b, R11c, R11d, X, n1, n2, and n3 are as defined herein, are provided. Uses of such compounds for modulating androgen receptor activity, imaging diagnostics in cancer and therapeutics, and methods for treatment of subjects in need thereof, including prostate cancer are also provided.
