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Pyrrolidol derivatives as ACC inhibitors
专利权人:
ALMIRALL; S.A.
发明人:
ESTEVE TRIAS, CRISTINA,BACH TAA, JORDI,MIR CEPEDA, MARTA
申请号:
ARP180103610
公开号:
AR113925A1
申请日:
2018.12.11
申请国别(地区):
AR
年份:
2020
代理人:
摘要:
Claim 1: a pyrethroid derivative which is a formula compound (1),a. Or a pharmaceutically acceptable salt, or oxidation, or a tautometer, or a stereoisomer, or a stereoisomer, or an isotope labeled derivative, wherein R1 shall be selected from a group consisting of hydrogen atoms, one set being cc283318383318324 linear or separator, one group being halotar cc28322138333137, or a linear or segregator; a. A c83216c83318321;; 8320 linear or separable aquatic biota, un - (ch832222) 8320318323 - (monocyclic ring chemistry group c833231832783278a);Un - (ch8322) 8320833183323 - (arilo c83322683318331832183838321); 8324 single ring or double ring;Un - (ch8322) 8320833183323 - (isomerization group of 4-7 members, including at least one heteroatom selected from n to o),Un - (ch8322) 8320833183323 - (a heteromorphic group of 5-14 monocyclic or biperiodic members containing at least one heteromorphic atom selected from n to o),a. One group - (ch832223231) 832431;One - (cr74919); r749521;a. Cyclopropyl compounds, arilo, isopropyl compounds and isopropyl compounds are not replaced or replaced by one or more substitutes selected from a halogen atom, a linear or separated matrix of c8331218838324 and an oxo group; R2 should be selected from a hydrogen atom, a halogen atom and a CN CN CN group; a. A set of c83216c83318324248 linear or laminized tar; R3 is a set of c83299c83318322;; 8320 linear or separate tar, in which tar is not replaced or replaced by one or more selected from halogen atoms, one hydroxyl group, one c838383316c8324 linear or laminized tar group;a. Alcoxi c83216c8331832626 and a c832118c83318324 or a linear or separated hydrogen group; r8308 was selected from a group consisting of hydrogen atoms and a c832183318324 linear or separated tar group; r830983309; r830218 was selected from a group consisting of hydrogen atoms and a c832183318324 group; a. C8332183318321;; 8320 linear or dissociative, un-o - (rental group c8321833121;; 8320 linear or dissociative);UN-O-(CH8
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