AGENTS ANTIPALUDIQUES INHIBITEURS DE LA DIHYDRO-OROTATE DÉSHYDROGÉNASE

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专利权人:

GLAXOSMITHKLINE INVESTIGACION Y DESARROLLO, S.L.;MONASH UNIVERSITY;UNIVERSITY OF WASHINGTON;BOARD OF REGENTS;MEDICINES FOR MALARIA VENTURE;BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM; THE UNIVERSITY OF TEXAS SYSTEM

发明人:

RATHOD, PRADIPSINH, K.,FLOYD, DAVID,BURROWS, JEREMY,MARWAHA, ALKA,GUJJAR, RAMESH,COTERON-LOPEZ, JOSE,PHILLIPS, MARGARET,CHARMAN, SUSAN, A.,MATTHEWS, DAVID

申请号：

EP10821105

公开号：

EP2483274A4

申请日:

2010.09.28

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

Inhibitors of parasitic dihydroorotate dehydrogenase enzyme (DHOD) are candidate therapeutics for treating malaria. Illustrative of such therapeutic agents include the compound: and a triazolopyrimidine class of compounds that conform to Formula IX: and their solvates, stereoisomers, tautomers and pharmaceutically acceptable salts.

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