Yingzhi Bi,Kenneth Gordon Carson,Giovanni Cianchetta,Michael Alan Green,Godwin Kumi,Alan Main,Yulian Zhang,Glenn Gregory Zipp
申请号：
US14483898
公开号：
US09403832B2
申请日:
2014.09.11
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Pyrazolo[1,5-a]pyrimidine-based compounds of the formula:are disclosed, wherein R1, R2 and R3 are defined herein. Compositions comprising the compounds and methods of their use to treat, manage and/or prevent diseases and disorders mediated by adaptor associated kinase 1 activity are also disclosed.
