Yingzhi Bi,Michael Walter Gardyan,Michael Alan Green,Godwin Kumi,Yulian Zhang
申请号:
US15145435
公开号:
US09862724B2
申请日:
2016.05.03
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Pyrazolo[1,5-a]pyrimidine-based compounds of the formula:are disclosed, wherein R1, R2 and R3 are defined herein. Compositions comprising the compounds and methods of their use to treat, manage and/or prevent diseases and disorders mediated by mediated by adaptor associated kinase 1 activity are also disclosed.