PYRAZOLO[1,5-a]PYRIMIDINE-BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE

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专利权人:

INC.;LEXICON PHARMACEUTICALS

发明人:

BI, YINGZHI,CARSON, KENNETH GORDON,CIANCHETTA, GIOVANNI,GREEN, MICHAEL ALAN,KUMI, GODWIN,MAIN, ALAN,ZHANG, YULIAN,ZIPP, GLENN GREGORY

申请号：

SG11201405561R

公开号：

SG11201405561RA

申请日:

2013.03.05

申请国别(地区):

SG

年份:

2014

代理人:

摘要：

Pyrazolo[1,5-a]pyrimidine-based compounds of the formula: are disclosed, wherein R1, R2 and R3 are defined herein. Compositions comprising the compounds and methods of their use to treat, manage and/or prevent diseases and disorders mediated by adaptor associated kinase 1 activity are also disclosed.

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中国工程科技知识中心

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