Kazuhiro Ito,Peter Strong,William Garth Rapeport,Peter John Murray,John King-Underwood,Jonathan Gareth Williams,Stuart Onions,Catherine Elisabeth Charron
申请号:
US14171198
公开号:
US09242960B2
申请日:
2014.02.03
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to a compound of formula (I):or a pharmaceutically acceptable salt thereof, including all stereoisomers and tautomers, which is an inhibitor of p38 mitogen-activated protein kinase enzymes (referred to herein as p38 MAP kinase inhibitors), particularly the alpha and gamma kinase sub-types thereof, and its use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, such as COPD.