William Garth Rapeport;Catherine Elisabeth Charron;Stuart Onions;Peter Strong;Kazuhiro Ito;Peter John Murray;John King-Underwood;Jonathan Gareth Williams
发明人:
Kazuhiro Ito,Peter Strong,William Garth Rapeport,Peter John Murray,John King-Underwood,Jonathan Gareth Williams,Stuart Onions,Catherine Elisabeth Charron
申请号：
US13262266
公开号：
US08642773B2
申请日:
2010.04.01
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to a compound of formula (I):or a pharmaceutically acceptable salt thereof, including all stereoisomers and tautomers, which is an inhibitor of p38 mitogen-activated protein kinase enzymes (referred to herein as p38 MAP kinase inhibitors), particularly the alpha and gamma kinase sub-types thereof, and its use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, such as COPD.
