Ito, Kazuhiro,Strong, Peter,Rapeport, William Garth,Murray, Peter John,King-Underwood, John,Williams, Jonathan Gareth,Onions, Stuart Thomas,Hirst, Simon Christopher,Taddei, David Michel Adrien,Charron
申请号：
AU2009326149
公开号：
AU2009326149B2
申请日:
2009.12.11
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The invention relates to compounds of formula (I): or a pharmaceutically acceptable salt thereof, including all stereoisomers, tautomers and isotopic derivatives thereof, which are inhibitors of p38 mitogen-activated protein kinase enzymes (referred to herein as p38 MAP kinase inhibitors), particularly the alpha and gamma kinase sub-types thereof, and their use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, such as COPD.
