ITO KAZUHIRO,RAPEPORT WILLIAM GARTH,KING-UNDERWOOD JOHN,ONIONS STUART,STRONG PETER,MURRAY PETER JOHN,WILLIAMS JONATHAN GARETH,CHARRON CATHERINE ELISABETH
申请号:
ZA201108048
公开号:
ZA201108048B
申请日:
2011.11.02
申请国别(地区):
ZA
年份:
2013
代理人:
摘要:
The present invention relates to a compound of formula (I): or a pharmaceutically acceptable salt thereof, including all stereoisomers and tautomers, which is an inhibitor of p38 mitogen-activated protein kinase enzymes (referred to herein as p38 MAP kinase inhibitors), particularly the alpha and gamma kinase sub-types thereof, and its use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, such as COPD.