VAN STRATEN, NICOLE CORINE RENEE,GERRITSMA, GERRITDINA GEZIENA,VAN DER VEEN, LARS ANDERS
申请号:
CA2606521
公开号:
CA2606521C
申请日:
2005.05.04
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention relates to dihydropyridine derivatives having generalformula (I) or a pharmaceutically acceptable salt thereof, wherein R1 is (1-6C)alkyl, (2-6C)alkenyl, (2-6C)alkynyl, phenyl, (1-5C)heteroaryl R2, R3 areindependently (1-4C)alkyl, (2-4C)alkenyl, (2-4C)alkynyl, (1-4C)alkoxy,(2~4C)alkenyloxy, (2-4C)alkynyloxy, halogen X is SO2, CH2, C(O) or X is absentR4 is (1-6C)alkyl, (2-6C)alkenyl, (2-6C)alkynyl, (3-6C)cycloalkyl, (3-6C)cycloalkenyl, (3-6C)cycloalkyl(1-4C)alkyl, (2-6C)heterocycloalkyl, (2-6C)heterocycloalkyl(1~4C)alkyl, (6-1 OC)aryl, (6-10C)aryl(1-4C)alkyl, (1-9C)heteroaryl or (1-9C)heteroaryl(1~4C)alkyl. The compounds are useful for thetreatment of fertility disorders.