POLYMORPHE CRISTALLIN D'ACETATE DE 15?-HYDROXY-OSATERONE

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专利权人:

LTD.;ASKA PHARMACEUTICAL CO.

发明人:

NAKAGAWA, TAKAYOSHI,HAYASHI, HIROYUKI,MIYAZAKI, KOICHI,IWASHITA, SHIGEKI

申请号：

CA3021179

公开号：

CA3021179A1

申请日:

2017.05.10

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

Provided is a crystalline polymorph A of 15ß-hydroxy-osaterone acetate having improved stabilities (storage stability, pulverization stability, and absorption property). Diffraction peaks characteristic of this crystalline polymorph A of 15ß-hydroxy-osaterone acetate, in a powder X-ray diffraction spectrum, appear at diffraction angles 2? of 9.6°±0.2°, 17.1°±0.2°, and 20.2°±0.2°. The crystalline polymorph A has a melting point of 280-283°C, and is a prismatic crystal.

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