CRYSTALLINE POLYMORPH OF 15B-HYDROXY-OSATERONE ACETATE

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专利权人:

LTD.;ASKA PHARMACEUTICAL CO.

发明人:

NAKAGAWA Takayoshi,HAYASHI Hiroyuki,MIYAZAKI Koichi,IWASHITA Shigeki

申请号：

SG11201809127P

公开号：

SG11201809127PA

申请日:

2017.05.10

申请国别(地区):

SG

年份:

2018

代理人:

摘要：

Provided is a crystalline polymorphic form A of 15 b-hydroxy-osaterone acetate having an improved stability (storage stability, pulverization stability, 5 and absorption characteristics). In a powder X-ray diffraction spectrum, characteristic diffraction peaks of the crystalline polymorphic form A of 15 b-hydroxy-osaterone acetate appear at diffraction angles 2q of 9.6° ± 0.2°, 17.1° ± 0.2°, and 20.2° ± 0.2°. 10 The crystalline polymorphic form A has a melting point of 280 to 283 °C and is a prism crystal.

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