Crystalline polymorph of 15ß-hydroxy-osaterone acetate

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专利权人:

Ltd.;ASKA Pharmaceutical Co.

发明人:

Nakagawa, Takayoshi,Hayashi, Hiroyuki,Miyazaki, Koichi,Iwashita, Shigeki

申请号：

AU2017264187

公开号：

AU2017264187A1

申请日:

2017.05.10

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

Provided is a crystalline polymorph A of 15β-hydroxy-osaterone acetate having improved stabilities (storage stability, pulverization stability, and absorption property). Diffraction peaks characteristic of this crystalline polymorph A of 15β-hydroxy-osaterone acetate, in a powder X-ray diffraction spectrum, appear at diffraction angles 2θ of 9.6°±0.2°, 17.1°±0.2°, and 20.2°±0.2°. The crystalline polymorph A has a melting point of 280-283°C, and is a prismatic crystal.

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